Search results for "experimental validation"
showing 10 items of 37 documents
Dynamic Response of a Rigital Displacement Motor Operating with Various Displacement Strategies
2019
Digital displacement technology has the potential of revolutionizing the performance of hydraulic piston pumps and motors. Instead of connecting each cylinder chamber to high and low pressure in conjunction with the shaft position, two electrically-controlled on/off valves are connected to each chamber. This allows for individual cylinder chamber control. Variable displacement can be achieved by using different displacement strategies, like for example the full stroke, partial stroke, or sequential partial stroke displacement strategy. Each displacement strategy has its transient and steady-state characteristics. This paper provides a detailed simulation analysis of the transient and steady…
Performance comparison of tubular linear induction motors with different primary winding connections
2014
This paper presents an experimental characterization and comparison of the performances achieved by a tubular linear induction motor (TLIM) prototype with different typologies of primary winding connections. In particular, three configurations are described: full-pitch star, 5/6 shortened pitch star and 5/6 shortened pitch double star. For this purpose, an experimental test bench at the SDESLAB laboratory (University of Palermo) has been set-up and the results obtained from the tests have allowed to identify which type of winding configuration can be chosen in dependence of the type of application intended for the motor. In addition, this experimental study is suitable for TLIM winding desi…
On the Efficacy of PCM to Shave Peak Temperature of Crystalline Photovoltaic Panels: An FDM Model and Field Validation
2013
The exploitation of renewable energy sources and specifically photovoltaic (PV) devices have been showing significant growth; however, for a more effective development of this technology it is essential to have higher energy conversion performances. PV producers often declare a higher efficiency respect to real conditions and this deviation is mainly due to the difference between nominal and real temperature conditions of the PV. In order to improve the solar cell energy conversion efficiency many authors have proposed a methodology to keep the temperature of a PV system lower: a modified crystalline PV system built with a normal PV panel coupled with a Phase Change Material (PCM) heat stor…
A semi-empirical multipurpose steady-state model of a fuel cell for household appliances
2013
In this paper, a multipurpose model of a proton exchange membrane fuel cell for household appliances is proposed. According to a conventional mathematical approach, the proposed model is derived from the physical and electro-chemical equations that rule the fuel cell behaviour. Differently from existing models, a parametric analysis is carried out and a few tunable parameters are accurately selected and identified. Furthermore, this paper proposes an innovative technique of unique model architecture which enables the designer to solve by himself the trade-off between complexity and accuracy on the basis of the specific applications. Three different choices could be performed by the designer…
Experimental validation of the BAC factor method for lighting systems
2017
In the last few years, many buildings have been equipped with Building Automation and Control (BAC) systems. BAC systems can be used to achieve a significant reduction of the electrical consumption and to have all the well acknowledged benefits from the daylight (e.g. occupant comfort, health, well-being and productivity). For this reason, Standard EN 15232 "Energy performance of buildings — Impact of Building Automation, Controls and Building Management" puts into evidence the importance of the presence of BAC and Technical Building Management (TBM) systems, suggests a classification of these systems, explains their main functionalities and presents a simplified method to estimate their im…
Molecular topology applied to the discovery of 1-benzyl-2-(3-fluorophenyl)-4-hydroxy-3-(3-phenylpropanoyl)-2H-pyrrole-5-one as a non-ligand-binding-p…
2014
We report the discovery of 1-benzyl-2-(3- fluorophenyl)-4-hydroxy-3-(3-phenylpropanoyl)-2H-pyrrole- 5-one as a novel non-ligand binding pocket (non-LBP) antagonist of the androgen receptor (AR) through the application of molecular topology techniques. This compound, validated through time-resolved fluorescence resonance energy transfer and fluorescence polarization biological assays, provides the basis for lead optimization and structure−activity relationship analysis of a new series of non-LBP AR antagonists. Induced-fit docking and molecular dynamics studies have been performed to establish a consistent hypothesis for the interaction of the new active molecule on the AR surface. Refereed/…
Pressure drop at low reynolds numbers in woven-spacer-filled channels for membrane processes: CFD prediction and experimental validation
2017
The energy consumption due to pumping power is a crucial issue in membrane processes. Spacers provide mechanical stability and promote mixing, yet increasing pressure drop. Woven spacers and their behaviour at low Reynolds numbers are less studied in the literature. Nevertheless, they are typical of some membrane technologies, as reverse electrodialysis (RED). RED is a promising technology for electric power generation by the chemical potential difference of two salt solutions within a stack equipped by selective ion-exchange membranes. The mechanical energy required for pumping the feed solutions, can dramatically reduce the net power output. In this work computational fluid dynamics (CFD)…
Classification of SD-OCT Volumes Using Local Binary Patterns: Experimental Validation for DME Detection
2016
International audience; This paper addresses the problem of automatic classification of Spectral Domain OCT (SD-OCT) data for automatic identification of patients with Diabetic Macular Edema (DME) versus normal subjects. Optical Coherence Tomography (OCT) has been a valuable diagnostic tool for DME, which is among the most common causes of irreversible vision loss in individuals with diabetes. Here, a classification framework with five distinctive steps is proposed and we present an extensive study of each step. Our method considers combination of various pre-processings in conjunction with Local Binary Patterns (LBP) features and different mapping strategies. Using linear and non-linear cl…
Experimental validation of a novel compact focusing scheme for future energy-frontier linear lepton colliders.
2014
A novel scheme for the focusing of high-energy leptons in future linear colliders was proposed in 2001 [ P. Raimondi and A. Seryi , Phys. Rev. Lett. 86 , 3779 ( 2001 ) ]. This scheme has many advantageous properties over previously studied focusing schemes, including being significantly shorter for a given energy and having a significantly better energy bandwidth. Experimental results from the ATF2 accelerator at KEK are presented that validate the operating principle of such a scheme by demonstrating the demagnification of a 1.3 GeV electron beam down to below 65 nm in height using an energy-scaled version of the compact focusing optics designed for the ILC collider.
MicroRNA profiling associated with non-small cell lung cancer: next generation sequencing detection, experimental validation, and prognostic value
2017
[EN] Background: The average five-year survival for non-small cell lung cancer (NSCLC) patients is approximately 15%. Emerging evidence indicates that microRNAs (miRNAs) constitute a new class of gene regulators in humans that may play an important role in tumorigenesis. Hence, there is growing interest in studying their role as possible new biomarkers whose expression is aberrant in cancer. Therefore, in this study we identified dysregulated miRNAs by next generation sequencing (NGS) and analyzed their prognostic value. Methods: Sequencing by oligo ligation detection technology was used to identify dysregulated miRNAs in a training cohort comprising paired tumor/normal tissue samples (N = …